William Jorgensen selected as laureate of the Citation 2021

William L. Jorgensen, Sterling Professor of Chemistry, has been selected as the recipient of the 2021 Citation for his influential contributions to the field of computational chemistry.

This distinction reflects the importance of Jorgensen’s work within the scientific community. Citation winners are selected based on an analysis of data from the Web of Science Research and Citation Database, which identifies influential research in the fields of chemistry, physics, physiology or science. medicine and economics.

London-based analytics firm Clarivate announced the selection of this year’s 16 winners on September 22. The laureates are researchers who have co-authored studies cited more than 2,000 times and whose work is considered “Nobel class”.

Whether an article is cited 2,000 times or more is a rarity, ”said David Pendlebury, senior citation analyst at the Institute for Scientific Information at Clarivate. “Highly cited authors of articles are typically members of national academies of sciences, hold leadership positions in universities and other research institutes, and have received many leading international awards in their fields.

Indeed, many of them have helped shape their fields of study. Some of these “scientific elites” go on to receive Nobel Prizes, each year demonstrating the association between citations in the literature, influence through a research community and peer review. “

Jorgensen’s pioneering work in computational chemistry and molecular design has included simulations of organic and enzymatic reactions, computer-aided drug design, as well as the synthesis and development of anti-HIV, anti-inflammatory and anti-cancer agents. .

He was honored for his “methods and studies in computational chemistry of organic and biomolecular systems in solution, contributing to the rational design and synthesis of drugs”.

Jorgensen has had four publications that have been cited over 2,000 times and had a total of over 90,000 citations during his career, according to Web of Science. (Google Scholar lists six of these articles for Jorgensen and 115,000 citations in total.)

Earlier this year, Jorgensen and his colleagues at Yale demonstrated the development of a new class of antiviral agents showing promise for the creation of novel COVID-19 therapies. The new compounds also have the potential to be effective against future coronaviruses.

Jorgensen joined Yale faculty in 1990. Among his many honors, he was elected to the National Academy of Sciences and is a member of the American Association for the Advancement of Science, American Academy of Arts and Sciences, from the American Chemical Society. , and the International Academy of Quantum Molecular Sciences. In 2015, Jorgensen won the prestigious Tetrahedron Prize for Creativity in Bioorganic and Medicinal Chemistry.

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